Manglik, Aashish: search on Z-Library

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1

Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms

BillesbÃ¸lle, Christian B., Azumaya, Caleigh M., Kretsch, Rachael C., Powers, Alexander S., Gonen, Shane, Schneider, Simon, Arvedson, Tara, Dror, Ron O., Cheng, Yifan, Manglik, Aashish

Journal:

Year:

2020

File:

PDF, 11.51 MB

2020

2

Nanobodies to Study G Protein–Coupled Receptor Structure and Function

Manglik, Aashish, Kobilka, Brian K., Steyaert, Jan

Journal:

Annual Review of Pharmacology

Year:

2017

Language:

english

File:

PDF, 4.12 MB

english, 2017

3

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

Manglik, Aashish, Kruse, Andrew C., Kobilka, Tong Sun, Thian, Foon Sun, Mathiesen, Jesper M., Sunahara, Roger K., Pardo, Leonardo, Weis, William I., Kobilka, Brian K., Granier, Sébastien

Journal:

Year:

2012

Language:

english

File:

PDF, 1.78 MB

english, 2012

4

Yeast surface display platform for rapid discovery of conformationally selective nanobodies

McMahon, Conor, Baier, Alexander S., Pascolutti, Roberta, Wegrecki, Marcin, Zheng, Sanduo, Ong, Janice X., Erlandson, Sarah C., Hilger, Daniel, Rasmussen, Søren G. F., Ring, Aaron M., Manglik, Aashish

Journal:

Nature Structural and Molecular Biology

Year:

2018

Language:

english

File:

PDF, 4.28 MB

english, 2018

5

Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling

Manglik, Aashish, Kim, Tae Hun, Masureel, Matthieu, Altenbach, Christian, Yang, Zhongyu, Hilger, Daniel, Lerch, Michael T., Kobilka, Tong Sun, Thian, Foon Sun, Hubbell, Wayne L., Prosser, R. Scott, Ko

Journal:

Year:

2015

Language:

english

File:

PDF, 1.88 MB

english, 2015

6

A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action

Stoeber, Miriam, Jullié, Damien, Lobingier, Braden T., Laeremans, Toon, Steyaert, Jan, Schiller, Peter W., Manglik, Aashish, von Zastrow, Mark

Journal:

Year:

2018

Language:

english

File:

PDF, 6.33 MB

english, 2018

7

Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling

Manglik, Aashish, Kim, Tae Hun, Masureel, Matthieu, Altenbach, Christian, Yang, Zhongyu, Hilger, Daniel, Lerch, Michael T., Kobilka, Tong Sun, Thian, Foon Sun, Hubbell, Wayne L., Prosser, R. Scott, Ko

Journal:

Year:

2015

Language:

english

File:

PDF, 65 KB

english, 2015

8

The Dynamic Process of β2-Adrenergic Receptor Activation

Nygaard, Rie, Zou, Yaozhong, Dror, Ron O., Mildorf, Thomas J., Arlow, Daniel H., Manglik, Aashish, Pan, Albert C., Liu, Corey W., Fung, Juan José, Bokoch, Michael P., Thian, Foon Sun, Kobilka, Tong Su

Journal:

Year:

2013

Language:

english

File:

PDF, 2.37 MB

english, 2013

9

A comparison of chemical shift sensitivity of trifluoromethyl tags: optimizing resolution in19F NMR studies of proteins

Ye, Libin, Larda, Sacha Thierry, Frank Li, Yi Feng, Manglik, Aashish, Prosser, R. Scott

Journal:

Journal of Biomolecular NMR

Year:

2015

Language:

english

File:

PDF, 652 KB

english, 2015

10

Molecular basis of opioid action: from structures to new leads

Manglik, Aashish

Journal:

Biological Psychiatry

Year:

2019

Language:

english

File:

PDF, 15.13 MB

english, 2019

11

Structure-based discovery of opioid analgesics with reduced side effects

Manglik, Aashish, Lin, Henry, Aryal, Dipendra K., McCorvy, John D., Dengler, Daniela, Corder, Gregory, Levit, Anat, Kling, Ralf C., Bernat, Viachaslau, Hübner, Harald, Huang, Xi-Ping, Sassano, Maria F

Journal:

Year:

2016

Language:

english

File:

PDF, 8.35 MB

english, 2016

12

Author Correction: Structural insights into Î¼-opioid receptor activation

Huang, Weijiao, Manglik, Aashish, Venkatakrishnan, A. J., Laeremans, Toon, Feinberg, Evan N., Sanborn, Adrian L., Kato, Hideaki E., Livingston, Kathryn E., Thorsen, Thor S., Kling, Ralf C., Granier, S

Journal:

Year:

2020

File:

PDF, 768 KB

2020

13

Propagation of conformational changes during μ-opioid receptor activation

Sounier, Rémy, Mas, Camille, Steyaert, Jan, Laeremans, Toon, Manglik, Aashish, Huang, Weijiao, Kobilka, Brian K., Déméné, Héléne, Granier, Sébastien

Journal:

Year:

2015

Language:

english

File:

PDF, 4.92 MB

english, 2015

14

Corrigendum: A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins

Chae, Pil Seok, Rasmussen, Søren G. F., Rana, Rohini R., Gotfryd, Kamil, Kruse, Andrew C., Manglik, Aashish, Cho, Kyung Ho, Nurva, Shailika, Gether, Ulrik, Guan, Lan, Loland, Claus J., Byrne, Bernadet

Journal:

Chemistry - A European Journal

Year:

2013

File:

PDF, 206 KB

2013

15

Inside Cover: A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins (Chem. Eur. J. 31/2012)

Prof. Pil Seok Chae, Prof. Søren G. F. Rasmussen, Rohini R. Rana, Kamil Gotfryd, Andrew C. Kruse, Aashish Manglik, Kyung Ho Cho, Shailika Nurva, Prof. Ulrik Gether, Prof. Lan Guan, Prof. Claus J. Lola

Journal:

Chemistry - A European Journal

Year:

2012

File:

PDF, 537 KB

2012

16

Structural insights into µ-opioid receptor activation

Huang, Weijiao, Manglik, Aashish, Venkatakrishnan, A. J., Laeremans, Toon, Feinberg, Evan N., Sanborn, Adrian L., Kato, Hideaki E., Livingston, Kathryn E., Thorsen, Thor S., Kling, Ralf C., Granier, S

Journal:

Year:

2015

Language:

english

File:

PDF, 4.66 MB

english, 2015

17

Structural basis for G protein-coupled receptor activation

Manglik, Aashish, Kruse, Andrew

Journal:

Year:

2017

Language:

english

File:

PDF, 10.13 MB

english, 2017

18

G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs)

Li, Lingyong, Homan, Kristoff T., Vishnivetskiy, Sergey A., Manglik, Aashish, Tesmer, John J. G., Gurevich, Vsevolod V., Gurevich, Eugenia V.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 6.96 MB

english, 2015

19

Allosteric coupling from G protein to the agonist-binding pocket in GPCRs

DeVree, Brian T., Mahoney, Jacob P., Vélez-Ruiz, Gisselle A., Rasmussen, Soren G. F., Kuszak, Adam J., Edwald, Elin, Fung, Juan-Jose, Manglik, Aashish, Masureel, Matthieu, Du, Yang, Matt, Rachel A., P

Journal:

Year:

2016

Language:

english

File:

PDF, 6.98 MB

english, 2016

20

Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor

Livingston, Kathryn E, Mahoney, Jacob P, Manglik, Aashish, Sunahara, Roger, Traynor, John R

Journal:

Year:

2018

Language:

english

File:

PDF, 15.02 MB

english, 2018

21

Stably Integrated luxCDABE for Assessment of Salmonella Invasion Kinetics

Flentie, Kelly N., Qi, Min, Gammon, Seth T., Razia, Yasmin, Lui, Felix, Marpegan, Luciano, Manglik, Aashish, Piwnica-Worms, David, McKinney, Jeffrey S.

Journal:

Molecular Imaging

Year:

2008

File:

PDF, 513 KB

2008

22

Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling

Staus, Dean P., Wingler, Laura M., Choi, Minjung, Pani, Biswaranjan, Manglik, Aashish, Kruse, Andrew C., Lefkowitz, Robert J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 821 KB

english, 2018

23

Structure of the δ-opioid receptor bound to naltrindole

Granier, Sébastien, Manglik, Aashish, Kruse, Andrew C., Kobilka, Tong Sun, Thian, Foon Sun, Weis, William I., Kobilka, Brian K.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.70 MB

english, 2012

24

Î²-Arrestin-Biased Angiotensin II Receptor Agonists for COVID-19

Manglik, Aashish, Wingler, Laura M., Rockman, Howard A., Lefkowitz, Robert J.

Journal:

Year:

2020

File:

PDF, 752 KB

2020

25

The Role of Ligands on the Equilibria Between Functional States of a G Protein-Coupled Receptor

Kim, Tae Hun, Chung, Ka Young, Manglik, Aashish, Hansen, Alexandar L., Dror, Ron O., Mildorf, Thomas J., Shaw, David E., Kobilka, Brian K., Prosser, R. Scott

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 2.59 MB

english, 2013

26

Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody

Ring, Aaron M., Manglik, Aashish, Kruse, Andrew C., Enos, Michael D., Weis, William I., Garcia, K. Christopher, Kobilka, Brian K.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.72 MB

english, 2013

27

The role of protein dynamics in GPCR function: insights from the β2AR and rhodopsin

Manglik, Aashish, Kobilka, Brian

Journal:

Current Opinion in Cell Biology

Year:

2014

Language:

english

File:

PDF, 1.51 MB

english, 2014

28

Applications of molecular replacement to G protein-coupled receptors

Kruse, Andrew C., Manglik, Aashish, Kobilka, Brian K., Weis, William I.

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

29

Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

Staus, Dean P., Strachan, Ryan T., Manglik, Aashish, Pani, Biswaranjan, Kahsai, Alem W., Kim, Tae Hun, Wingler, Laura M., Ahn, Seungkirl, Chatterjee, Arnab, Masoudi, Ali, Kruse, Andrew C., Pardon, Els

Journal:

Year:

2016

Language:

english

File:

PDF, 4.52 MB

english, 2016

30

ADULT CŒLIAC DISEASE

Manglik, Aashish, Kobilka, Brian

Journal:

Year:

1969

Language:

english

File:

PDF, 358 KB

english, 1969

31

Crystal structure of the human σ1 receptor

Schmidt, Hayden R., Zheng, Sanduo, Gurpinar, Esin, Koehl, Antoine, Manglik, Aashish, Kruse, Andrew C.

Journal:

Year:

2016

Language:

english

File:

PDF, 9.46 MB

english, 2016

32

A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins

Prof. Pil Seok Chae, Prof. Søren G. F. Rasmussen, Rohini R. Rana, Kamil Gotfryd, Andrew C. Kruse, Aashish Manglik, Kyung Ho Cho, Shailika Nurva, Prof. Ulrik Gether, Prof. Lan Guan, Prof. Claus J. Lola

Journal:

Chemistry - A European Journal

Year:

2012

Language:

english

File:

PDF, 624 KB

english, 2012

33

Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

Shukla, Arun K., Manglik, Aashish, Kruse, Andrew C., Xiao, Kunhong, Reis, Rosana I., Tseng, Wei-Chou, Staus, Dean P., Hilger, Daniel, Uysal, Serdar, Huang, Li-Yin, Paduch, Marcin, Tripathi-Shukla, Pra

Journal:

Year:

2013

Language:

english

File:

PDF, 1.47 MB

english, 2013

34

Development of an antibody fragment that stabilizes GPCR/G-protein complexes

Maeda, Shoji, Koehl, Antoine, Matile, Hugues, Hu, Hongli, Hilger, Daniel, Schertler, Gebhard F. X., Manglik, Aashish, Skiniotis, Georgios, Dawson, Roger J. P., Kobilka, Brian K.

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 2.48 MB

english, 2018

35

Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit

Zhang, Yunxiao, Lu, Wan-Jin, Bulkley, David P., Liang, Jiahao, Ralko, Arthur, Han, Shuo, Roberts, Kelsey J., Li, Anping, Cho, Wonhwa, Cheng, Yifan, Manglik, Aashish, Beachy, Philip A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 2.20 MB

2020

36

Activation and allosteric modulation of a muscarinic acetylcholine receptor

Kruse, Andrew C., Ring, Aaron M., Manglik, Aashish, Hu, Jianxin, Hu, Kelly, Eitel, Katrin, Hübner, Harald, Pardon, Els, Valant, Celine, Sexton, Patrick M., Christopoulos, Arthur, Felder, Christian C.,

Journal:

Year:

2013

Language:

english

File:

PDF, 4.19 MB

english, 2013

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